Since the launch of the “Formulating for Efficacy™, the Software” program, many people have asked for a demonstration of the software. After all, seeing is believing. Therefore, a series of screencasts (video’s) was created in which the ways of working of this computer program is being explained and illustrated.

Just press play to start the first screencast. The subsequent screencasts will be played in the correct order.

Outline of the screencasts

The Ingredients Selection screencast discusses how you can enter the ingredients that appear in your formulation. An ingredient is defined as anything that can dissolve your active ingredient, so emollients, preservatives, sun filters, etc. Only emulsifiers should not be added in this page. Thickeners can also be ignored. Also how to enter more complicated emollients that are mixtures of pure ingredients is shown.

The Actives screencast explains how to enter your active ingredient as well as the phase ratios and concentration of your active. This is also the place where you need to enter whether your active is supplied as a pure solid active or diluted or dissolved in something.

The Formulation page of the software offers many possibilities.

  • In Formulation part 1, the differences between optimizing to Active, Target Concentration and Skin are discussed and illustrated.
  • In Formulation part 2, the meaning of the important parameters SFG (skin formulation gap) and AFG (active formulation gap) are explained and illustrated.
  • In Formulation part 3, the formulation method “Optimize to Target Concentration” is explained. This is the method most closely linked to traditional skin penetration theories by maximizing the thermodynamic activity of the active in your formulation.
  • In Formulation part 4, the various options on how to “Optimize to stratum corneum” are being shown and explained. Here, you see how to start a formulation from scratch or how to modify existing formulations. Also, what you need to do if you do not like a recommendation made by the program to disable this emollient. Finally, you also learn what to do if you do insist in having a certain emollient at a certain percentage in your formulation.
  • And finally, in Formulation part 5, some little tricks are discussed to overcome strange mixtures such as mineral oil and water. After all, the program only sees numbers but formulation science is more than just numbers. But with the help of this program, you can get to excellent formulations a lot faster.

If still in doubt, don’t hesitate to write to us at

We wish you all the very best in your attempts to “Formulate for Efficacy™”.